The temporal explorer who returns to the base

We study here the problem of exploring a temporal graph when the underlying graph is a star. The aim of the exploration problem in a temporal star is finding a temporal walk which starts and finishes at the center of the star, and visits all leaves. We present a systematic study of the computational complexity of this problem, depending on the number k of time points where each edge can be present in the graph. We distinguish between the decision version StarExp(k), asking whether a complete exploration exists, and the maximization version MaxStarExp(k), asking for an exploratkion of the greatest possible number of edges. We fully characterize MaxStarExp(k) in terms of complexity. We also partially characterize StarExp(k), showing that it is in P for k 5 . Finally, we partially characterize classes of “random” temporal stars which are, asymptotically almost surely, yes-instances and no-instances for StarExp(k)

Ephemeral networks with random availability of links: diameter and connectivity

In this work we consider temporal networks, the links of which are available only at random times (randomly available temporal networks). Our networks are {\em ephemeral}: their links appear sporadically, only at certain times, within a given maximum time (lifetime of the net). More specifically, our temporal networks notion concerns networks, whose edges (arcs) are assigned one or more random discrete-time labels drawn from a set of natural numbers. The labels of an edge indicate the discrete moments in time at which the edge is available. In such networks, information (e.g., messages) have to follow temporal paths, i.e., paths, the edges of which are assigned a strictly increasing sequence of labels. We first examine a very hostile network: a clique, each edge of which is known to be available only one random time in the time period {1,2, ..., n} (n is the number of vertices). How fast can a vertex send a message to all other vertices in such a network? To answer this, we define the notion of the Temporal Diameter for the random temporal clique and prove that it is Θ(log n) with high probability and in expectation. In fact, we show that information dissemination is very fast with high probability even in this hostile network with regard to availability. This result is similar to the results for the random phone-call model. Our model, though, is weaker. Our availability assumptions are different and randomness is provided only by the input. We show here that the temporal diameter of the clique is crucially affected by the clique's lifetime, a, e.g., when a is asymptotically larger than the number of vertices, n, then the temporal diameter must be Ω(a/nlog n ). We, then, consider the least number, r, of random points in time at which an edge is available, in order to guarantee at least a temporal path between any pair of vertices of the network (notice that the clique is the only network for which just one instance of availability per edge, even non-random, suffices for this). We show that r is Ω(log n) even for some networks of diameter 2. Finally, we compare this cost to an (optimal) deterministic allocation of labels of availability that guarantees a temporal path between any pair of vertices. For this reason, we introduce the notion of the Price of Randomness and we show an upper bound for general networks

Temporal vertex cover with a sliding time window.

Modern, inherently dynamic systems are usually characterized by a network structure which is subject to discrete changes over time. Given a static underlying graph, a temporal graph can be represented via an assignment of a set of integer time-labels to every edge, indicating the discrete time steps when this edge is active. While most of the recent theoretical research on temporal graphs focused on temporal paths and other “path-related” temporal notions, only few attempts have been made to investigate “non-path” temporal problems. In this paper we introduce and study two natural temporal extensions of the classical problem VERTEX COVER. We present a thorough investigation of the computational complexity and approximability of these two temporal covering problems. We provide strong hardness results, complemented by approximation and exact algorithms. Some of our algorithms are polynomial-time, while others are asymptotically almost optimal under the Exponential Time Hypothesis (ETH) and other plausible complexity assumptions

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Ephemeral networks with random availability of links: The case of fast networks

We consider here a model of temporal networks, the links of which are available only at certain moments in time, chosen randomly from a subset of the positive integers. We define the notion of the Temporal Diameter of such networks. We also define fast and slow such temporal networks with respect to the expected value of their temporal diameter. We then provide a partial characterisation of fast random temporal networks. We also define the critical availability as a measure of periodic random availability of the links of a network, required to make the network fast. We finally give a lower bound as well as an upper bound on the (critical) availability

The temporal explorer who returns to the base

In this paper we study the problem of exploring a temporal graph (i.e. a graph that changes over time), in the fundamental case where the underlying static graph is a star on n vertices. The aim of the exploration problem in a temporal star is to find a temporal walk which starts at the center of the star, visits all leaves, and eventually returns back to the center. We present here a systematic study of the computational complexity of this problem, depending on the number k of time-labels that every edge is allowed to have; that is, on the number k of time points where each edge can be present in the graph. To do so, we distinguish between the decision version STAREXP(k) , asking whether a complete exploration of the instance exists, and the maximization version MAXSTAREXP(k) of the problem, asking for an exploration schedule of the greatest possible number of edges in the star. We fully characterize MAXSTAREXP(k) and show a dichotomy in terms of its complexity: on one hand, we show that for both k=2 and k=3 , it can be efficiently solved in O(nlogn) time; on the other hand, we show that it is APX-complete, for every k≥4 (does not admit a PTAS, unless P = NP, but admits a polynomial-time 1.582-approximation algorithm). We also partially characterize STAREXP(k) in terms of complexity: we show that it can be efficiently solved in O(nlogn) time for k∈{2,3} (as a corollary of the solution to MAXSTAREXP(k) , for k∈{2,3} ), but is NP-complete, for every k≥6

The complexity of optimal design of temporally connected graphs

We study the design of small cost temporally connected graphs, under various constraints. We mainly consider undirected graphs of n vertices, where each edge has an associated set of discrete availability instances (labels). A journey from vertex u to vertex v is a path from u to v where successive path edges have strictly increasing labels. A graph is temporally connected iff there is a (u, v)-journey for any pair of vertices u, v, u ≠ v. We first give a simple polynomial-time algorithm to check whether a given temporal graph is temporally connected. We then consider the case in which a designer of temporal graphs can freely choose availability instances for all edges and aims for temporal connectivity with very small cost; the cost is the total number of availability instances used. We achieve this via a simple polynomial-time procedure which derives designs of cost linear in n. We also show that the above procedure is (almost) optimal when the underlying graph is a tree, by proving a lower bound on the cost for any tree. However, there are pragmatic cases where one is not free to design a temporally connected graph anew, but is instead given a temporal graph design with the claim that it is temporally connected, and wishes to make it more cost-efficient by removing labels without destroying temporal connectivity (redundant labels). Our main technical result is that computing the maximum number of redundant labels is APX-hard, i.e., there is no PTAS unless P = NP. On the positive side, we show that in dense graphs with random edge availabilities, there is asymptotically almost surely a very large number of redundant labels. A temporal design may, however, be minimal, i.e., no redundant labels exist. We show the existence of minimal temporal designs with at least nlogn labels

Temporal vertex cover with a sliding time window

Modern, inherently dynamic systems are usually characterized by a network structure which is subject to discrete changes over time. Given a static underlying graph, a temporal graph can be represented via an assignment of a set of integer time-labels to every edge, indicating the discrete time steps when this edge is active. While most of the recent theoretical research on temporal graphs focused on temporal paths and other “path-related” temporal notions, only few attempts have been made to investigate “non-path” temporal problems. In this paper we introduce and study two natural temporal extensions of the classical problem VERTEX COVER. We present a thorough investigation of the computational complexity and approximability of these two temporal covering problems. We provide strong hardness results, complemented by approximation and exact algorithms. Some of our algorithms are polynomial-time, while others are asymptotically almost optimal under the Exponential Time Hypothesis (ETH) and other plausible complexity assumptions

Predictors for anastomotic leak, postoperative complications, and mortality after right colectomy for cancer: Results from an international snapshot audit

Background: A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking. Objective: This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy. Design: This was a snapshot observational prospective study. Setting: The study was conducted as a multicenter international study. Patients: The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients. Main Outcome Measures: Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method. Results: Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p 65 0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041). Limitations: This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors. Conclusions: Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery